- NAD(P)+ + H2O ADP-ribose(P) + nicotinamide
This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is NAD(P)+ glycohydrolase. Other names in common use include nicotinamide adenine dinucleotide (phosphate) nucleosidase, triphosphopyridine nucleotidase, NAD(P) nucleosidase, NAD(P)ase, and nicotinamide adenine dinucleotide (phosphate) glycohydrolase. This enzyme participates in nicotinate and nicotinamide metabolism.
- IUBMB entry for 18.104.22.168
- BRENDA references for 22.214.171.124 (Recommended.)
- PubMed references for 126.96.36.199
- PubMed Central references for 188.8.131.52
- Google Scholar references for 184.108.40.206
- ALIVISATOS SG, WOOLLEY DW (1956). "Solubilization and purification of the diphosphopyridine nucleotidase from beef spleen". J. Biol. Chem. 219: 823&ndash, 32. PMID 13319302.
- ZATMAN LJ, KAPLAN NO, COLOWICK SP (1953). "Inhibition of spleen diphosphopyridine nucleotidase by nicotinamide, an exchange reaction". J. Biol. Chem. 200: 197&ndash, 212. PMID 13034774.
- Zatman LJ, Kaplan NO, Colowick SP and Ciotti MM (1953). "Formation of the isonicotinic acid hydrazide analog of DPN". J. Am. Chem. Soc. 75: 3293&ndash, 3294.
- The CAS registry number for this enzyme class is 9025-46-1.
Gene Ontology (GO) codes
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