Myelophthisis
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Synonyms: Myelophthisic anemia
Overview
Myelophthisis refers to the displacement of hemopoietic bone-marrow tissue into the peripheral blood, either by fibrosis, tumors or granulomas. A myelophthisic blood smear is one which contains nucleated red blood cells, granulocyte precursors, and teardrop-shaped erythrocytes. This condition is also known as Myelophthisic anemia. Myelophthisis can be observed in cancers that that involve the bone marrow such as leukemia, lymphoma, and myeloma or metastatic carcinoma.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
