Mycobacterium gordonae
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| Mycobacterium gordonae | ||||||||||||||
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| Mycobacterium gordonae Bojalil et al. 1962, ATCC 14470 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Mycobacterium gordonae
Description
Gram-positive, nonmotile and moderate to long acid-fast rods.
- Commonly found in tap water and soil. Casual resident in human sputum and gastric lavage specimens.
Colony characteristics
- Smooth, with yellow or orange scotochromogenic colonies. Even though they are scotochromogenic pigment is intensified by growing in continuous light.
Physiology
- Growth on Löwenstein-Jensen medium and Middlebrook 7H10 agar within 7 or more days at 37°C (optimal 25°C).
- Does not grow in the presence of ethambutol (1mg/l), isoniazid (10mg/l) and sodium chloride (5%).
Differential characteristics
- A commercial hybridisation assay (AccuProbe) to identify M. gordonae exists.
- Intraspecies variability in 16S rDNA sequences
Pathogenesis
- Rarely if ever implicated in disease processes unless patients are immunocompromised.
- Biosafety level 1
Type Strain
Strain ATCC 14470 = CCUG 21801 = CCUG 21811 = CIP 104529 = DSM 44160 = JCM 6382 = NCTC 10267.
Treatment
Antimicrobial regimen
- M. gordonae [1]
- Preferred regimen: Ethambutol OR Rifabutin OR Clarithromycin OR Linezolid OR Fluoroquinolones
References
- ↑ Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). "An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases". American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.
- Bojalil et al. 1962. Adansonian classification of mycobacteria. Journal of General Microbiology, 28, 333-346.