Masoprocol

Masoprocol
Systematic (IUPAC) name
4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
Identifiers
CAS number	500-38-9
ATC code	L01XX10
PubChem	71398
DrugBank	DB00179
Chemical data
Formula	C18H22O4
Mol. mass	302.365 g/mol
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	Very low
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	B(US)
Legal status
Routes	Topical

WikiDoc Resources for Masoprocol
Articles
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Evidence Based Medicine
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Clinical Trials
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Guidelines / Policies / Govt
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News
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Commentary
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Definitions
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Patient Resources / Community
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Healthcare Provider Resources
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Continuing Medical Education (CME)
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International
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Business
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Experimental / Informatics
List of terms related to Masoprocol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

Also called nordihydroguaiaretic acid, NDGA, and actinex.

Mechanism

Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.

It is a lipoxygenase inhibitor.

External links

• MedlinePlus Drug Information
• Actinex entry in the public domain NCI Cancer Dictionary