Masoprocol
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Masoprocol
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Systematic (IUPAC) name | |
4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol | |
Identifiers | |
CAS number | |
ATC code | L01 |
PubChem | |
DrugBank | |
Chemical data | |
Formula | C18H22O4 |
Mol. mass | 302.365 g/mol |
SMILES | & |
Pharmacokinetic data | |
Bioavailability | Very low |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
B(US) |
Legal status | |
Routes | Topical |
WikiDoc Resources for Masoprocol |
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Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Masoprocol at Clinical Trials.gov Clinical Trials on Masoprocol at Google
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Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Masoprocol
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News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Masoprocol Discussion groups on Masoprocol Patient Handouts on Masoprocol Directions to Hospitals Treating Masoprocol Risk calculators and risk factors for Masoprocol
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Healthcare Provider Resources |
Causes & Risk Factors for Masoprocol |
Continuing Medical Education (CME) |
International |
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Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.
Also called nordihydroguaiaretic acid, NDGA, and actinex.
Mechanism
Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.
It is a lipoxygenase inhibitor.[1]
References
External links
- MedlinePlus Drug Information
- Actinex entry in the public domain NCI Cancer Dictionary