Macroglobulin

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


A macroglobulin is a plasma globulin of high molecular weight.

Elevated levels of macroglobulins (macroglobulinemia) is seen in diseases such as Waldenström macroglobulinemia.

Other macroglobulins include alpha-2 macroglobulin, which is elevated in nephrotic syndrome, diabetes, severe burns, and other conditions, while a deficiency is associated with chronic obstructive pulmonary disease.

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