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Mindbomb homolog 1 (Drosophila)
Symbol(s) MIB1; DIP-1; DKFZp686I0769; DKFZp761M1710; FLJ90676; MGC129659; MGC129660; MIB; ZZANK2; ZZZ6
External IDs OMIM: 608677 MGI2443157 Homologene10810
RNA expression pattern




More reference expression data

Human Mouse
Entrez 57534 225164
Ensembl ENSG00000101752 ENSMUSG00000024294
Uniprot Q86YT6 Q3TSS1
Refseq NM_020774 (mRNA)
NP_065825 (protein)
XM_976932 (mRNA)
XP_982026 (protein)
Location Chr 18: 17.58 - 17.7 Mb Chr 18: 10.73 - 10.81 Mb
Pubmed search [1] [2]

Mindbomb homolog 1 (Drosophila), also known as MIB1, is a human gene.[1]


Further reading

  • Nagase T, Kikuno R, Ishikawa KI; et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65–73. PMID 10718198. 
  • Wang Z, Tseng CP, Pong RC; et al. (2002). "The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2.". J. Biol. Chem. 277 (15): 12622–31. PMID 11812785. doi:10.1074/jbc.M110568200. 
  • Jin Y, Blue EK, Dixon S; et al. (2003). "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK.". J. Biol. Chem. 277 (49): 46980–6. PMID 12351649. doi:10.1074/jbc.M208585200. 
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932. doi:10.1073/pnas.242603899. 
  • Itoh M, Kim CH, Palardy G; et al. (2003). "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta.". Dev. Cell. 4 (1): 67–82. PMID 12530964. 
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285. 
  • Henshall DC, Schindler CK, So NK; et al. (2004). "Death-associated protein kinase expression in human temporal lobe epilepsy.". Ann. Neurol. 55 (4): 485–94. PMID 15048887. doi:10.1002/ana.20001. 
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMID 15489334. doi:10.1101/gr.2596504. 
  • Yoo KW, Kim EH, Jung SH; et al. (2006). "Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.". FEBS Lett. 580 (18): 4409–16. PMID 16857196. doi:10.1016/j.febslet.2006.07.009. 
  • Song R, Koo BK, Yoon KJ; et al. (2007). "Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.". J. Biol. Chem. 281 (47): 36391–400. PMID 17003037. doi:10.1074/jbc.M606601200. 
  • Zhang L, Nephew KP, Gallagher PJ (2007). "Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes.". J. Biol. Chem. 282 (16): 11795–804. PMID 17324930. doi:10.1074/jbc.M610430200. 
  • Yakut T, Gutenberg A, Bekar A; et al. (2007). "Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas.". Oncol. Rep. 17 (5): 1037–43. PMID 17390041. 
  • van der Avoort IA, van der Laak JA, Paffen A; et al. (2007). "MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva.". Mod. Pathol. 20 (7): 770–8. PMID 17464313. doi:10.1038/modpathol.3800796.