MAPK4

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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Mitogen-activated protein kinase 4 is an enzyme that in humans is encoded by the MAPK4 gene.[1][2]

Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.[2]

The Arabidopsis MAPK4 is important in signalling [3]

References

  1. Li L, Wysk M, Gonzalez FA, Davis RJ (Feb 1994). "Genomic loci of human mitogen-activated protein kinases". Oncogene. 9 (2): 647–9. PMID 8290275.
  2. 2.0 2.1 "Entrez Gene: MAPK4 mitogen-activated protein kinase 4".
  3. Petersen M, Brodersen P, Naested H, Andreasson E, Lindhart U, Johansen B, Nielsen HB, Lacy M, Austin MJ, Parker JE, Sharma SB, Klessig DF, Martienssen R, Mattsson O, Jensen AB & Mundy J (2000). "Arabidopsis MAP Kinase 4 Negatively Regulates Systemic Acquired Resistance". Cell. 103 (7): 1111–1120. doi:10.1016/S0092-8674(00)00213-0. PMID 11163186.

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Further reading



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