Lymphocytopenia causes

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Lymphocytopenia Microchapters



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Differentiating Lymphocytopenia from other Diseases

Epidemiology and Demographics

Risk Factors


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.


Common causes of lymphocytopenia include side effects of drugs that cause platelet changes. Additional common causes include congenital and acquired hematological conditions.


Common Causes

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning Dimethyl fumarate
Dental No underlying causes
Dermatologic Aplasia cutis congenital, Cartilage hair hypoplasia
Drug Side Effect Aclarubicin, Alefacept, Alemtuzumab, Bendamustine, Blinatumomab, Cabozantinib, Chemotherapy, Chloramphenicol, Cladribine, Corticosteroids, Dinutuximab, Doxorubicin, Elotuzumab, Eribulin, Everolimus, Exemestane, Fludarabine, Idarubicin, Idelalisib, Ixabepilone, Legionella pneumophila, Linezolid, Lorcaserin, Olaparib, Olsalazine, Omacetaxine mepesuccinate, Oxaliplatin, Pamidronate, Pazopanib, Pentostatin, Rituximab, Saxagliptin, Sorafenib, Sunitinib malate, Temsirolimus, Vinblastine
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic Intestinal lymphangiectasis
Genetic Mckusick type metaphyseal chondrodysplasia, Purine nucleoside phosphorylase (pnp) deficiency
Hematologic Adenosine deaminase deficiency, Antithymocyte globulin, Aplastic anemia, Common variable hypogammaglobulinaemia, De vaal syndrome, Hodgkin's disease, Human granulocytic ehrlichiosis, Human monocytotropic ehrlichiosis, Interferon beta, Legionella pneumophila, Leukemia, Lymphangiectasis, Pancytopenia, Schimke immunoosseous dysplasia, Waldmann disease, Wiskott-aldrich syndrome
Iatrogenic Chemotherapy, Radiation therapy
Infectious Disease Acute viral nasopharyngitis, Aids, Epstein-barr virus, chronic, Hiv-1 disease, Human granulocytic ehrlichiosis, Human monocytotropic ehrlichiosis, Influenza, Tuberculosis, Typhoid fever, Viral hepatitis
Musculoskeletal/Orthopedic Myelodysplastic syndrome
Neurologic Ataxia telangiectasia
Nutritional/Metabolic Malnutrition
Obstetric/Gynecologic No underlying causes
Oncologic Leukemia, Myelodysplastic syndrome
Ophthalmologic Reticular dysgenesis
Overdose/Toxicity No underlying causes
Psychiatric Stress
Pulmonary Sarcoidosis, Severe acute respiratory syndrome, Tuberculosis, Typhoid fever,
Renal/Electrolyte Spondyloepiphyseal dysplasia -- nephrotic syndrome
Rheumatology/Immunology/Allergy Nezelof syndrome, Sarcoidosis, Systemic lupus erythematosus, Wiskott-aldrich syndrome
Sexual Aids, Hiv-1 disease, Viral hepatitis
Trauma Excessive physical exercise, Stress
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order