Lepirudin
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| Lepirudin
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| Systematic (IUPAC) name | |
| ? | |
| Identifiers | |
| CAS number | |
| ATC code | B01 |
| PubChem | ? |
| DrugBank | |
| Chemical data | |
| Formula | C288H448N80O110S6 |
| Mol. mass | 6983.5 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 100% |
| Metabolism | ? |
| Half life | ~1.3 hours |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
B(US) |
| Legal status | |
| Routes | SQ or IV |
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WikiDoc Resources for Lepirudin | |
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Most recent articles on Lepirudin | |
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Media | |
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Evidence Based Medicine | |
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Clinical Trials | |
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Ongoing Trials on Lepirudin at Clinical Trials.gov Clinical Trials on Lepirudin at Google
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Guidelines / Policies / Govt | |
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US National Guidelines Clearinghouse on Lepirudin
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Books | |
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News | |
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Commentary | |
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Definitions | |
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Patient Resources / Community | |
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Patient resources on Lepirudin Discussion groups on Lepirudin Directions to Hospitals Treating Lepirudin Risk calculators and risk factors for Lepirudin
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Healthcare Provider Resources | |
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Causes & Risk Factors for Lepirudin | |
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Continuing Medical Education (CME) | |
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International | |
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Business | |
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Experimental / Informatics | |
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Overview
Lepirudin (Refludan ®) is an anticoagulant which functions as a direct thrombin inhibitor.
It is derived from the saliva of the medicinal leech Hirudo medicinalis.
External links
- Hirudo Medicinalis TURKEY, Supplier of Hirudo Medicinalis
- Hirudo Medicinalis TURKEY
- DDB 30082
- Smythe M, Stephens J, Koerber J, Mattson J (2005). "A comparison of lepirudin and argatroban outcomes.". Clin Appl Thromb Hemost 11 (4): 371-4. PMID 16244762.
- "Predictive factors for thrombosis and major bleeding in an observational study in 181 patients with heparin-induced thrombocytopenia treated with lepirudin.". Blood. PMID 16690967.
- Lubenow N, Eichler P, Lietz T, Greinacher A (2005). "Lepirudin in patients with heparin-induced thrombocytopenia - results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3.". J Thromb Haemost 3 (11): 2428-36. PMID 16241940.
- http://www.refludan.com/product/index.htm
WikiDoc Research Resources for Lepirudin | |
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| Articles on Lepirudin | Most recent articles on Lepirudin • Most cited articles on Lepirudin • Review articles on Lepirudin • Articles on Lepirudin in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Lepirudin | Powerpoint slides on Lepirudin • Images of Lepirudin • Photos of Lepirudin • Podcasts & MP3s on Lepirudin • Videos on Lepirudin |
| Evidence Based Medicine Regarding Lepirudin | Cochrane Collaboration on Lepirudin • Bandolier on Lepirudin • TRIP on Lepirudin |
| Cost Effectiveness of Lepirudin | Cost Effectiveness of Lepirudin |
| Clinical Trials Involving Lepirudin | Ongoing Trials on Lepirudin at Clinical Trials.gov • Trial results on Lepirudin • Clinical Trials on Lepirudin at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Lepirudin | US National Guidelines Clearinghouse on Lepirudin • NICE Guidance on Lepirudin • NHS PRODIGY Guidance • FDA on Lepirudin • CDC on Lepirudin |
| Textbook Information on Lepirudin | Books and Textbook Information on Lepirudin |
| Pharmacology Resources on Lepirudin | Dosing of Lepirudin • Drug interactions with Lepirudin • Side effects of Lepirudin • Allergic reactions to Lepirudin • Overdose information on Lepirudin • Carcinogenicity information on Lepirudin • Lepirudin in pregnancy • Pharmacokinetics of Lepirudin • |
| Genetics, Pharmacogenomics, and Proteinomics of Lepirudin | Genetics of Lepirudin • Pharmacogenomics of Lepirudin • Proteomics of Lepirudin |
| Newstories on Lepirudin | Lepirudin in the news • Be alerted to news on Lepirudin • News trends on Lepirudin |
| Commentary on Lepirudin | Blogs on Lepirudin |
| Patient Resources on Lepirudin | Patient resources on Lepirudin • Discussion groups on Lepirudin • Patient Handouts on Lepirudin • Directions to Hospitals Treating Lepirudin • Risk calculators and risk factors for Lepirudin |
| Healthcare Provider Resources on Lepirudin | Symptoms of Lepirudin • Causes & Risk Factors for Lepirudin • Diagnostic studies for Lepirudin • Treatment of Lepirudin |
| Continuing Medical Education (CME) Programs on Lepirudin | CME Programs on Lepirudin |
| International Resources on Lepirudin | Lepirudin en Espanol • Lepirudin en Francais |
| Business Resources on Lepirudin | Lepirudin in the Marketplace • Patents on Lepirudin |
| Informatics Resources on Lepirudin | List of terms related to Lepirudin |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
