Large cell

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Overview

Large cell is a term used in oncology. It doesn't refer to a particular type of cell; rather it refers to cells that are larger than would be normally expected for that type. It is frequently used when describing lymphoma and lung cancer.

It was more frequently used in the past than it is used today, when doctors often could tell little about a cell other than its size, and it was used for classification systems such as the "Working Formulation" for lymphoma. As such, the term lives on in the names of many conditions, even when the size of the cell is no longer one of the most important diagnostic criteria.

The phrase "Giant cell" is also frequently used, especially with carcinoma.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .