Langerhans cell histiocytosis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

MRI may be helpful in the diagnosis of Langerhans cell histiocytosis. Findings on T1 weighted MRI imaging suggestive of Langerhans cell histiocytosis include a well-defined, isointense, brain lesion associated with reactive dural enhancement.[1][2]

MRI

  • MRI may be helpful in the diagnosis of Langerhans cell histiocytosis.[1][2]
  • MRI image characteristics observed among medulloblastoma patients include:
  • T1 weighted image demonstrates:
  • An isointense lesion associated with reactive dural enhancement
  • T2 weighted image demonstrates:
  • Heterogeneously hyperintense lesion
  • T1 weighted image iwth gadolinium contrast demonstrates:
  • Marked contrast enhancement

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References

  1. 1.0 1.1 1.2 1.3 1.4 Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016
  2. 2.0 2.1 Khung S, Budzik JF, Amzallag-Bellenger E, Lambilliote A, Soto Ares G, Cotten A; et al. (2013). "Skeletal involvement in Langerhans cell histiocytosis". Insights Imaging. 4 (5): 569–79. doi:10.1007/s13244-013-0271-7. PMC 3781243. PMID 23907805.


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