Lactobacillus acidophilus

Jump to: navigation, search
Lactobacillus acidophilus
L. acidophilus bacteria near vaginal squamous epithelial cells)
L. acidophilus bacteria near vaginal squamous epithelial cells)
Scientific classification
Kingdom: Bacteria
Division: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: L. acidophilus
Binomial name
Lactobacillus acidophilus
(Moro 1900)
Hansen & Mocquot 1970

WikiDoc Resources for Lactobacillus acidophilus


Most recent articles on Lactobacillus acidophilus

Most cited articles on Lactobacillus acidophilus

Review articles on Lactobacillus acidophilus

Articles on Lactobacillus acidophilus in N Eng J Med, Lancet, BMJ


Powerpoint slides on Lactobacillus acidophilus

Images of Lactobacillus acidophilus

Photos of Lactobacillus acidophilus

Podcasts & MP3s on Lactobacillus acidophilus

Videos on Lactobacillus acidophilus

Evidence Based Medicine

Cochrane Collaboration on Lactobacillus acidophilus

Bandolier on Lactobacillus acidophilus

TRIP on Lactobacillus acidophilus

Clinical Trials

Ongoing Trials on Lactobacillus acidophilus at Clinical

Trial results on Lactobacillus acidophilus

Clinical Trials on Lactobacillus acidophilus at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Lactobacillus acidophilus

NICE Guidance on Lactobacillus acidophilus


FDA on Lactobacillus acidophilus

CDC on Lactobacillus acidophilus


Books on Lactobacillus acidophilus


Lactobacillus acidophilus in the news

Be alerted to news on Lactobacillus acidophilus

News trends on Lactobacillus acidophilus


Blogs on Lactobacillus acidophilus


Definitions of Lactobacillus acidophilus

Patient Resources / Community

Patient resources on Lactobacillus acidophilus

Discussion groups on Lactobacillus acidophilus

Patient Handouts on Lactobacillus acidophilus

Directions to Hospitals Treating Lactobacillus acidophilus

Risk calculators and risk factors for Lactobacillus acidophilus

Healthcare Provider Resources

Symptoms of Lactobacillus acidophilus

Causes & Risk Factors for Lactobacillus acidophilus

Diagnostic studies for Lactobacillus acidophilus

Treatment of Lactobacillus acidophilus

Continuing Medical Education (CME)

CME Programs on Lactobacillus acidophilus


Lactobacillus acidophilus en Espanol

Lactobacillus acidophilus en Francais


Lactobacillus acidophilus in the Marketplace

Patents on Lactobacillus acidophilus

Experimental / Informatics

List of terms related to Lactobacillus acidophilus

Lactobacillus acidophilus is one of several bacteria in the genus Lactobacillus. It is in some countries sometimes used commercially together with Streptococcus salivarius and Lactobacillus delbrueckii ssp. bulgaricus in the production of acidophilus-type yogurt. Also known as the Boas-Oppler bacillus after Ismar Isidor Boas, a German gastroenterologist (1858-1938) and Bruno Oppler (-1932) a German physician from Breslau.

Lactobacillus acidophilus gets its name from lacto- meaning milk, -bacillus meaning rod-like in shape, and acidophilus meaning acid-loving. This bacterium thrives in more acidic environments than most related microorganisms (pH 4-5 or lower) and grows best at 45 degrees Celsius. L. acidophilus occurs naturally in the human and animal gastrointestinal tract, mouth, and vagina.[1] L. acidophilus ferments lactose into lactic acid, like many (but not all) lactic acid bacteria. Certain related species (known as heterofermentive) also produce ethanol, carbon dioxide, and acetic acid this way. L. acidophilus itself (a homofermentative microorganism) produces only lactic acid. Like many bacteria, L. acidophilus can be killed by excess heat, moisture, or direct sunlight.

Health benefits

Some strains of L. acidophilus may be considered a probiotic or "friendly" bacteria.[2] These types of healthy bacteria inhabit the intestines and vagina and protect against some unhealthy organisms. The breakdown of nutrients by L. acidophilus produces lactic acid, hydrogen peroxide, and other byproducts that make the environment hostile for undesired organisms. L. acidophilus also tends to consume the nutrients many other microorganisms depend on, thus outcompeting possibly harmful bacteria in the digestive tract. During digestion, L. acidophilus also assists in the production of niacin, folic acid, and pyridoxine. L. acidophilus can assist in bile deconjugation, separating amino acids from bile acids, which can then be recycled by the body.[3]

Some research has indicated L. acidophilus may provide additional health benefits, including improved gastrointestinal function, a boosted immune system, and a decrease in the frequency of vaginal yeast infections. Some people report L. acidophilus provides relief from indigestion and diarrhea.[4] A University of Nebraska study found that feed supplemented with L. acidophilus and fed to cattle resulted in a 61% reduction of Escherichia coli 0157:H7. Research has indicated L. acidophilus may be helpful reducing serum cholesterol levels.[5]

L. acidophilus is part of the normal vaginal flora.[6] The acid produced by L. acidophilus in the vagina helps to control the growth of the fungus Candida albicans, helping to prevent vaginal yeast infections. The same beneficial effect has been observed in cases of oral or gastrointestinal Candidiasis infections. Certain spermicides and contraceptive creams can kill L. acidophilus in the vagina, clearing the path to possible yeast infections.

Antibiotics taken orally will also kill beneficial bacteria like L. acidophilus. After a course of antibiotic therapy, patients are occasionally instructed to take an L. acidophilus treatment in order to recolonize the gastrointestinal tract.

L. acidophilus is often sold in health stores in pill or powder form as a nutritional supplement. Research on the nutritional benefits of taking L. acidophilus supplements is inconsistent and inconclusive. Most such claims boil down to a link between L. acidophilus and a possible decrease in the incidence of certain diseases, including yeast infections, gastrointestinal disorders, and a weakened immune system. Most researchers agree further study is needed before substantiating many of these claims.


  1. "Bacteria Genomes - LACTOBACILLUS ACIDOPHILUS". European Bioinformatics Institute. Retrieved 2007-08-22.
  2. Ljungh A, Wadström T (2006). "Lactic acid bacteria as probiotics". Curr Issues Intest Microbiol. 7 (2): 73–89. PMID 16875422.
  3. Gilliland S, Speck M (1977). "Deconjugation of bile acids by intestinal lactobacilli". Appl Environ Microbiol. 33 (1): 15–8. PMID 13710.
  4. de Roos N, Katan M (2000). "Effects of probiotic bacteria on diarrhea, lipid metabolism, and carcinogenesis: a review of papers published between 1988 and 1998". Am J Clin Nutr. 71 (2): 405–11. PMID 10648252.
  5. Anderson J, Gilliland S (1999). "Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans" (PDF). J Am Coll Nutr. 18 (1): 43–50. PMID 10067658.
  6. Forsum U, Holst E, Larsson P, Vasquez A, Jakobsson T, Mattsby-Baltzer I (2005). "Bacterial vaginosis--a microbiological and immunological enigma". APMIS. 113 (2): 81–90. PMID 15723682.

External links

da:Lactobacillus acidophilus de:Lactobacillus acidophilus he:לקטובצילוס אצידופילוס it:Lactobacillus acidophilus nl:Lactobacillus acidophilus