Isofuran

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Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted tetrahydrofuran ring. The concentration of oxygen affects this process; at elevated oxygen concentrations, the formation of isofurans is favored whereas the formation of isoprostanes is disfavored.[1]

References

  1. Roberts, LJ 2nd and Fessel, JP (2004 Mar). "The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation". Chem Phys Lipids. 128 ((1-2)): 173-86. doi:10.1111/j.1750-3639.2005.tb00511.x. Retrieved 2007-01-05. Check date values in: |year= (help) PMID: 15037162


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