Inappropriate sinus tachycardia medical therapy

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Inappropriate sinus tachycardia Microchapters

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Pathophysiology

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Differentiating Inappropriate Sinus Tachycardia from other Medical Conditions

Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Medical Therapy

Pharmacotherapy

Treatments in the form of pharmacological therapy or catheter ablation are available, although it is currently difficult to treat successfully.

Beta Blockers

In so far as the pathophysiology of IST involves abnormal sensitivity to adrenaline, betaa-blockers can be helpful.

Calcium Channel Blockers

Although calcium channel blockers slow conduction through the AV node, they have been marginally effective in the treatment of IST.

Ivabradine

A new selective sinus node inhibitor Ivabradine is also being used to treat IST.

Treatments Related to Dysautonomia and POTS

In so far as the underlying pathophysiology may involve a dysautonomia and features of Postural orthostatic tachycardia syndrome (POTS), some therapies more commonly used to treat these disorders have been tried:

POTS and dysautonomia have been associated with decreases in blood volume, and this drug promotes sodium retention.

Midodrine increases vasoconstriction, and prevents falls in blood pressure.

SSRIs have proven effective in treating some patients with dysautonomia.

References


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