Immunoglobulin allotype

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The allotype affects the constant region (labeled CL and CH1-3 in the diagram.)

In immunology, an immunoglobulin allotype is the allele of the antibody chains found in the individual.

To reduce risk of transplant rejection, tissue typing is used to try to match donors and recipients with the same or similar allotypes.

The most important types are Gm (heavy chain) and Km (light chain).

See also

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