Immune complex

Jump to navigation Jump to search
Immune Complex Diseases

WikiDoc Resources for Immune complex

Articles

Most recent articles on Immune complex

Most cited articles on Immune complex

Review articles on Immune complex

Articles on Immune complex in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Immune complex

Images of Immune complex

Photos of Immune complex

Podcasts & MP3s on Immune complex

Videos on Immune complex

Evidence Based Medicine

Cochrane Collaboration on Immune complex

Bandolier on Immune complex

TRIP on Immune complex

Clinical Trials

Ongoing Trials on Immune complex at Clinical Trials.gov

Trial results on Immune complex

Clinical Trials on Immune complex at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Immune complex

NICE Guidance on Immune complex

NHS PRODIGY Guidance

FDA on Immune complex

CDC on Immune complex

Books

Books on Immune complex

News

Immune complex in the news

Be alerted to news on Immune complex

News trends on Immune complex

Commentary

Blogs on Immune complex

Definitions

Definitions of Immune complex

Patient Resources / Community

Patient resources on Immune complex

Discussion groups on Immune complex

Patient Handouts on Immune complex

Directions to Hospitals Treating Immune complex

Risk calculators and risk factors for Immune complex

Healthcare Provider Resources

Symptoms of Immune complex

Causes & Risk Factors for Immune complex

Diagnostic studies for Immune complex

Treatment of Immune complex

Continuing Medical Education (CME)

CME Programs on Immune complex

International

Immune complex en Espanol

Immune complex en Francais

Business

Immune complex in the Marketplace

Patents on Immune complex

Experimental / Informatics

List of terms related to Immune complex

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

An immune complex is formed from the integral binding of an antibody to a soluble antigen. The bound antigen acting as a specific epitope, bound to an antibody is referred to as a singular immune complex. After an antigen-antibody reaction, the immune complexes can be subject to any of a number of responses, including complement deposition, opsonization, phagocytosis, or processing by proteases. Red blood cells carrying CR1-receptors on their surface may bind C3b-decorated immune complexes and transport them to phagocytes, mostly in liver and spleen, and return back to the general circulation.

Immune complexes may themselves cause disease when they are deposited in organs, e.g. in certain forms of vasculitis. This is the third form of hypersensitivity in the Gell-Coombs classification, called Type III hypersensitivity.

Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and Sjögren's syndrome.

External links

ca:Complex immunitari de:Antigen-Antikörper-Reaktion nl:Immuuncomplex


Template:WikiDoc Sources