Complement deficiency

(Redirected from Hypocomplementemia)
Jump to navigation Jump to search
Complement deficiency
ICD-10 D84.1
ICD-9 279.8
OMIM 217000 120820, 120900, 610102
DiseasesDB 1847 Template:DiseasesDB2, Template:DiseasesDB2, Template:DiseasesDB2, Template:DiseasesDB2

WikiDoc Resources for Complement deficiency

Articles

Most recent articles on Complement deficiency

Most cited articles on Complement deficiency

Review articles on Complement deficiency

Articles on Complement deficiency in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Complement deficiency

Images of Complement deficiency

Photos of Complement deficiency

Podcasts & MP3s on Complement deficiency

Videos on Complement deficiency

Evidence Based Medicine

Cochrane Collaboration on Complement deficiency

Bandolier on Complement deficiency

TRIP on Complement deficiency

Clinical Trials

Ongoing Trials on Complement deficiency at Clinical Trials.gov

Trial results on Complement deficiency

Clinical Trials on Complement deficiency at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Complement deficiency

NICE Guidance on Complement deficiency

NHS PRODIGY Guidance

FDA on Complement deficiency

CDC on Complement deficiency

Books

Books on Complement deficiency

News

Complement deficiency in the news

Be alerted to news on Complement deficiency

News trends on Complement deficiency

Commentary

Blogs on Complement deficiency

Definitions

Definitions of Complement deficiency

Patient Resources / Community

Patient resources on Complement deficiency

Discussion groups on Complement deficiency

Patient Handouts on Complement deficiency

Directions to Hospitals Treating Complement deficiency

Risk calculators and risk factors for Complement deficiency

Healthcare Provider Resources

Symptoms of Complement deficiency

Causes & Risk Factors for Complement deficiency

Diagnostic studies for Complement deficiency

Treatment of Complement deficiency

Continuing Medical Education (CME)

CME Programs on Complement deficiency

International

Complement deficiency en Espanol

Complement deficiency en Francais

Business

Complement deficiency in the Marketplace

Patents on Complement deficiency

Experimental / Informatics

List of terms related to Complement deficiency

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Hypocomplementemia

Overview

Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins.[1]

The disorders can be divided into two categories:

  • Disorders of the proteins that act to activate the complement system (such as C3) can lead to an underactive response, causing greater susceptibility to infections.

Because there are redundancies in the immune system, many complement disorders are never diagnosed. A recent study estimated that less than 10% are identified.[2]

Hypocomplementemia

The term "hypocomplementemia" is a more general term used to describe decreased complement levels.[3] The term "secondary complement disorder" is sometimes used to refer to low complement levels that are not directly due to a genetic cause but secondary to another medical condition.[4]

These levels can be used to distinguish conditions:

See also

References

  1. Sherwood L. Gorbach; John G. Bartlett; Neil R. Blacklow (2004). Infectious diseases. Lippincott Williams & Wilkins. pp. 11–. ISBN 978-0-7817-3371-7. Retrieved 30 May 2010.
  2. Sjöholm AG, Jönsson G, Braconier JH, Sturfelt G, Truedsson L (2006). "Complement deficiency and disease: an update". Mol. Immunol. 43 (1–2): 78–85. doi:10.1016/j.molimm.2005.06.025. PMID 16026838.
  3. Template:DorlandsDict
  4. http://emedicine.medscape.com/article/136368-overview

Template:Lymphoid and complement immunodeficiency