Hypernatremia historical perspective

Jump to: navigation, search

Hypernatremia Microchapters

Home

Patient Information

Overview

Historical perspective

Classification

Pathophysiology

Causes

Differentiating Hypernatremia from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

CT

MRI

Other Diagnostic Studies

Other Imaging Findings

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Case Studies

Case #1

Hypernatremia historical perspective On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hypernatremia historical perspective

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hypernatremia historical perspective

CDC on Hypernatremia historical perspective

Hypernatremia historical perspective in the news

Blogs on Hypernatremia historical perspective

Directions to Hospitals Treating Hypernatremia

Risk calculators and risk factors for Hypernatremia historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

In 1858, Claude Bernard, French physiologist first proposed a direct relationship between the central nervous system and renal excretion of osmotically active solutes. In 1913, Jungmann and Meyer in Germany induced polyuria and increased urinary salt excretion in animals through medullary lesion. In 1950, Peters, Welt, and co-workers described few patients with encephalitis, hypertensive intracranial hemorrhage, and bulbar poliomyelitis who presented with severe dehydration and hypernatremia.

Historical Perspective

The historical perspective of hypernatremia is as follows:[1][2][3][4]

Discovery

  • In 1952, Welt and colleagues presented patients with cerebral lesions (including trauma, tumor, and infection) and severe hypernatremia with clinical dehydration but no potassium retention.

References

  1. J. Barcroft & H. Straub (1910). "The secretion of urine". The Journal of physiology. 41 (3–4): 145–167. PMID 16993045. Unknown parameter |month= ignored (help)
  2. Czerny, A (1935). Ergebnisse der Inneren Medizin und Kinderheilkunde : Achtundvierzigster Band. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 9783642906701.
  3. J. P. PETERS, L. G. WELT, E. A. H. SIMS, J. ORLOFF & J. NEEDHAM (1950). "A salt-wasting syndrome associated with cerebral disease". Transactions of the Association of American Physicians. 63: 57–64. PMID 14855556.
  4. L. G. WELT, D. W. SELDIN, W. P. NELSON, W. J. GERMAN & J. P. PETERS (1952). "Role of the central nervous system in metabolism of electrolytes and water". A.M.A. archives of internal medicine. 90 (3): 355–378. PMID 14952060. Unknown parameter |month= ignored (help)

Linked-in.jpg