Hyper-IgM syndrome type 3

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Hyper-IgM syndrome type 3
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Immunoglobulin M
ICD-10 D80.5
ICD-9 279.05
OMIM 606843
eMedicine ped/2457 
MeSH D053306

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Hyper-IgM syndrome type 3 is a form of Hyper IgM syndrome characterized by mutations of the CD40 gene. In this type, B cells cannot receive the signal from T cells to switch classes.





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