Hygromycin-B kinase

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In enzymology, a hygromycin-B kinase (EC 2.7.1.119) is an enzyme that catalyzes the chemical reaction

ATP + hygromycin B ADP + 7"-O-phosphohygromycin

Thus, the two substrates of this enzyme are ATP and hygromycin B, whereas its two products are ADP and 7''-O-phosphohygromycin.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:hygromycin-B 7"-O-phosphotransferase. This enzyme is also called hygromycin B phosphotransferase.

References

  • IUBMB entry for 2.7.1.119
  • BRENDA references for 2.7.1.119 (Recommended.)
  • PubMed references for 2.7.1.119
  • PubMed Central references for 2.7.1.119
  • Google Scholar references for 2.7.1.119
  • Zalacain M, Pardo JM, Jimenez A (1987). "Purification and characterization of a hygromycin B phosphotransferase from Streptomyces hygroscopicus". Eur. J. Biochem. 162: 419&ndash, 22. PMID 3026811.

External links

The CAS registry number for this enzyme class is 88361-67-5.

Gene Ontology (GO) codes


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