Human respiratory syncytial virus causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Bassel Almarie M.D.[2]

Overview

Influenza infection is caused by the influenza virus that belong to the family Orthomyxoviridae. Three types of influenza virus have been reported to cause clinical illness in humans: types A, B, and C. Influenza virus can be found in humans, as well as in poultry, pigs, and bats.

Taxonomy

  • The scientific name of the virus is respiratory syncytial virus (hRSV)
    • Other names include human orthopneumovirus or respiratory syncytial virus (RSV)[1].
  • Member of the Pneumoviridae family and Orthopneumovirus genus.
  • Enveloped, negative sense, single stranded RNA virus[2].
  • Main subtypes are A and B. Most evidence suggests no difference in disease severity between both subtypes[3].
  • Lineage: Viruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales (negative-sense genome single-stranded RNA viruses) > Pneumoviridae > Orthopneumovirus[1].
  • Natural hosts for hRSV are humans and chimpanzees[4].
  • Transmission directly through large droplets via nasal or oral secretions or indirectly through contact with contaminated surfaces[5][6].

References

  1. 1.0 1.1 "www.ncbi.nlm.nih.gov".
  2. Rey-Jurado E, Kalergis AM (2017). "Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia-Implications for Vaccine Design". Int J Mol Sci. 18 (3). doi:10.3390/ijms18030556. PMC 5372572. PMID 28273842.
  3. Devincenzo JP (2004). "Natural infection of infants with respiratory syncytial virus subgroups A and B: a study of frequency, disease severity, and viral load". Pediatr Res. 56 (6): 914–7. doi:10.1203/01.PDR.0000145255.86117.6A. PMID 15470202.
  4. "Respiratory Syncytial Virus (RSV) - ScienceDirect".
  5. Hall CB, Douglas RG (1981). "Modes of transmission of respiratory syncytial virus". J Pediatr. 99 (1): 100–3. doi:10.1016/s0022-3476(81)80969-9. PMID 7252646.
  6. Hall CB (2000). "Nosocomial respiratory syncytial virus infections: the "Cold War" has not ended". Clin Infect Dis. 31 (2): 590–6. doi:10.1086/313960. PMID 10987726.

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