Gapicomine
| |
| Gapicomine
| |
| Systematic (IUPAC) name | |
| 1-Pyridin-4-yl-N-(pyridin-4-ylmethyl)methanamine | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C12H13N3 |
| Mol. mass | 199.25 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
off market (was used in EU countries) |
| Routes | oral (tablet) |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Gapicomine (INN) is a coronary vasodilator. It has been withdrawn from the market in the countries it was used in.[1]
Also, gapicomine is a major component in the drug bicordin.[2]
History
Gapicomine was discovered in 1970 by Polish chemist Stanisław Biniecki. It was first published about in an article of The Polish Journal of Medicine and Pharmacy describing the derivative drug bicordin in 1974.[3]
References
- ↑ Gapicomine Monograph, The Index Nominum. Retrieved on 2008-03-31.
- ↑ Bicordin, PubChem. Retrieved on 2008-03-31.
- ↑ Samochowiec L, Wójcicki J, Gregorczyk K, Szmatloch E. (1974). "Bicordin--a new drug in the treatment of coronary heart disease.". Mater Med Pol.: 298-300. PMID 4453155.
Vasodilators used in cardiac diseases (C01D) | |
|---|---|
| Nitrates | Glyceryl trinitrate • Isosorbide dinitrate • Isosorbide mononitrate • Molsidomine • Pentaerythritol tetranitrate |
| Quinolone vasodilators | Flosequinan |
| Others | Itramin tosilate • Prenylamine • Oxyfedrine • Benziodarone • Carbocromen • Hexobendine • Etafenone • Heptaminol • Imolamine • Dilazep • Trapidil • Molsidomine • Efloxate • Cinepazet • Cloridarol • Nicorandil • Linsidomine • Nesiritide • Gapicomine |
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