Gabriel-Colman rearrangement

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The Gabriel-Colman rearrangement is the chemical reaction of phthalimidoacetic esters (2) with strong base to form substituted isoquinolines (3).[1][2][3][4]

References

  1. Gabriel, S.; Colman, J. Ber. 1900, 33, 980 & 996 & 2630.
  2. Gabriel, S.; Colman, J. Ber. 1902, 35, 2421.
  3. Allen, C. F. H. Chem. Rev. 1950, 47, 275. (Review)
  4. Hill, J. H. M. J. Org. Chem. 1965, 30, 620.

See also


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