Combined hyperlipidemia

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Combined hyperlipidemia
ICD-10 E78.4
ICD-9 272.4

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WikiDoc Resources for Combined hyperlipidemia

Articles

Most recent articles on Combined hyperlipidemia

Most cited articles on Combined hyperlipidemia

Review articles on Combined hyperlipidemia

Articles on Combined hyperlipidemia in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Combined hyperlipidemia

Images of Combined hyperlipidemia

Photos of Combined hyperlipidemia

Podcasts & MP3s on Combined hyperlipidemia

Videos on Combined hyperlipidemia

Evidence Based Medicine

Cochrane Collaboration on Combined hyperlipidemia

Bandolier on Combined hyperlipidemia

TRIP on Combined hyperlipidemia

Clinical Trials

Ongoing Trials on Combined hyperlipidemia at Clinical Trials.gov

Trial results on Combined hyperlipidemia

Clinical Trials on Combined hyperlipidemia at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Combined hyperlipidemia

NICE Guidance on Combined hyperlipidemia

NHS PRODIGY Guidance

FDA on Combined hyperlipidemia

CDC on Combined hyperlipidemia

Books

Books on Combined hyperlipidemia

News

Combined hyperlipidemia in the news

Be alerted to news on Combined hyperlipidemia

News trends on Combined hyperlipidemia

Commentary

Blogs on Combined hyperlipidemia

Definitions

Definitions of Combined hyperlipidemia

Patient Resources / Community

Patient resources on Combined hyperlipidemia

Discussion groups on Combined hyperlipidemia

Patient Handouts on Combined hyperlipidemia

Directions to Hospitals Treating Combined hyperlipidemia

Risk calculators and risk factors for Combined hyperlipidemia

Healthcare Provider Resources

Symptoms of Combined hyperlipidemia

Causes & Risk Factors for Combined hyperlipidemia

Diagnostic studies for Combined hyperlipidemia

Treatment of Combined hyperlipidemia

Continuing Medical Education (CME)

CME Programs on Combined hyperlipidemia

International

Combined hyperlipidemia en Espanol

Combined hyperlipidemia en Francais

Business

Combined hyperlipidemia in the Marketplace

Patents on Combined hyperlipidemia

Experimental / Informatics

List of terms related to Combined hyperlipidemia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


In medicine, combined hyperlipidemia (or -aemia) is a commonly occurring form of hypercholesterolemia (elevated cholesterol levels) characterised by increased LDL and triglyceride concentrations, often accompanied by decreased HDL. On lipoprotein electrophoresis (a test now rarely performed) it shows as a hyperlipoproteinemia type IIB.

The elevated triglyceride levels (>5 mmol/l) are generally due to an increase in VLDL (very low density lipoprotein), a class of lipoprotein that is prone to cause atherosclerosis.

Types

There are roughly two forms of this lipid disorder:

Treatment

Both conditions are treated with fibrate drugs, which act on the peroxisome proliferator-activated receptors (PPARs), specifically PPARα, to decrease free fatty acid production.

Statin drugs, especially the synthetic statins (atorvastatin and rosuvastatin) can decrease LDL levels by increasing hepatic reuptake of LDL due to increased LDL-receptor expression.



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