End-diastolic volume
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In cardiovascular physiology, end-diastolic volume (EDV) is the volume of blood in a ventricle at the end of filling (diastole). Because greater EDVs cause greater distention of the ventricle, EDV is often used synonymously with preload, which refers to the length of the sarcomeres in cardiac muscle prior to contraction (systole). An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole (stroke volume).
Because nearly two-thirds of the blood in the systemic circulation is stored in the venous system, end-diastolic volume is closely related to venous compliance. Increasing venous compliance elevates the capacitance of the veins, reducing venous return and therefore end-diastolic volume. Decreasing venous compliance has the opposite effect. For example, activation of the baroreceptor reflex (occurring, for instance, in acute hemorrhage) causes venoconstriction, which decreases venous compliance, improves venous return, and therefore increases end-diastolic volume.
See also
WikiDoc Research Resources for End-diastolic volume | |
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| Articles on End-diastolic volume | Most recent articles on End-diastolic volume • Most cited articles on End-diastolic volume • Review articles on End-diastolic volume • Articles on End-diastolic volume in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on End-diastolic volume | Powerpoint slides on End-diastolic volume • Images of End-diastolic volume • Photos of End-diastolic volume • Podcasts & MP3s on End-diastolic volume • Videos on End-diastolic volume |
| Evidence Based Medicine Regarding End-diastolic volume | Cochrane Collaboration on End-diastolic volume • Bandolier on End-diastolic volume • TRIP on End-diastolic volume |
| Cost Effectiveness of End-diastolic volume | Cost Effectiveness of End-diastolic volume |
| Clinical Trials Involving End-diastolic volume | Ongoing Trials on End-diastolic volume at Clinical Trials.gov • Trial results on End-diastolic volume • Clinical Trials on End-diastolic volume at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding End-diastolic volume | US National Guidelines Clearinghouse on End-diastolic volume • NICE Guidance on End-diastolic volume • NHS PRODIGY Guidance • FDA on End-diastolic volume • CDC on End-diastolic volume |
| Textbook Information on End-diastolic volume | Books and Textbook Information on End-diastolic volume |
| Pharmacology Resources on End-diastolic volume | Dosing of End-diastolic volume • Drug interactions with End-diastolic volume • Side effects of End-diastolic volume • Allergic reactions to End-diastolic volume • Overdose information on End-diastolic volume • Carcinogenicity information on End-diastolic volume • End-diastolic volume in pregnancy • Pharmacokinetics of End-diastolic volume • |
| Genetics, Pharmacogenomics, and Proteinomics of End-diastolic volume | Genetics of End-diastolic volume • Pharmacogenomics of End-diastolic volume • Proteomics of End-diastolic volume |
| Newstories on End-diastolic volume | End-diastolic volume in the news • Be alerted to news on End-diastolic volume • News trends on End-diastolic volume |
| Commentary on End-diastolic volume | Blogs on End-diastolic volume |
| Patient Resources on End-diastolic volume | Patient resources on End-diastolic volume • Discussion groups on End-diastolic volume • Patient Handouts on End-diastolic volume • Directions to Hospitals Treating End-diastolic volume • Risk calculators and risk factors for End-diastolic volume |
| Healthcare Provider Resources on End-diastolic volume | Symptoms of End-diastolic volume • Causes & Risk Factors for End-diastolic volume • Diagnostic studies for End-diastolic volume • Treatment of End-diastolic volume |
| Continuing Medical Education (CME) Programs on End-diastolic volume | CME Programs on End-diastolic volume |
| International Resources on End-diastolic volume | End-diastolic volume en Espanol • End-diastolic volume en Francais |
| Business Resources on End-diastolic volume | End-diastolic volume in the Marketplace • Patents on End-diastolic volume |
| Informatics Resources on End-diastolic volume | List of terms related to End-diastolic volume |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
