Diphtheria differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Respiratory diphtheria must be differentiated from respiratory tract or other infections that present with fever, neck swelling, cough and/or pharyngeal exudates. Cutaneous diphtheria must be differentiated from other bacterial and fungal causes of skin ulceration.

Differentiating diphtheria from other diseases

Differentiating respiratory diphtheria from other diseases

A group of respiratory diseases can present with symptoms such as fever, sore throat, pharyngeal exudates and/or neck swelling, which may mimic the symptoms of a diphtheria infection. These include:[1]

Differentiating cutaneous diphtheria from other diseases

Cutaneous diphtheria due to Corynebacterium diphtheria must be differentiated from other bacterial and fungal diseases that present with a shallow ulcer on the skin:[2]

References

  1. Center for Disease Control and Prevention https://www.cdc.gov/diphtheria/downloads/dip-cklist-diag.pdf Accessed on Oct. 7, 2016.
  2. Zeegelaar JE, Faber WR (2008). "Imported tropical infectious ulcers in travelers". Am J Clin Dermatol. 9 (4): 219–32. PMID 18572973.



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