Diffuse esophageal spasm history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]

Overview

The hallmark of DES is esophageal dysphagia for both solids and liquids and chest pain. Symptom onset is sudden, intermittent and non-progressive in nature. Chest pain usually retrosternal in location, which is intense and squeezing in nature and may be mistaken for Angina. Difficulty swallowing, is sometimes related to specific substances like red wine, very cold or hot liquid.

History and Symptoms

History

Primary DES is less common than secondary DES. Patients with DES may have a positive history of:[1][2]

Common Symptoms

Common symptoms of DES include:

  • Symptom onset is sudden, intermittent and non-progressive in nature.
  • Chest pain usually retrosternal in location, which is intense and squeezing in nature and may be mistaken for Angina.
  • Difficulty swallowing, sometimes related to specific substances like red wine, very cold or hot liquid.
  • Regurgitation of swallowed food.
  • Odynophagia for both solids and liquids.

Less Common Symptoms

Less common symptoms of DES include

  • Weight loss
  • Heartburn
  • Symptoms related to secondary diseases.
    • Raynaud's phenomenon (RP) is seen in DES associated with scleroderma. However, degree of esophageal motility dysfunction cannot be predicted based on RP.[3]

References

  1. Herbella FA, Raz DJ, Nipomnick I, Patti MG (2009). "Primary versus secondary esophageal motility disorders: diagnosis and implications for treatment". J Laparoendosc Adv Surg Tech A. 19 (2): 195–8. doi:10.1089/lap.2008.0317. PMID 19260789.
  2. Strader SL (2001). "Esophageal motor disorders: achalasia and esophageal spasm". J Am Acad Nurse Pract. 13 (11): 502–7, quiz 508-10. PMID 11930515.
  3. Hurwitz AL, Duranceau A, Postlethwait RW (1976). "Esophageal dysfunction and Raynaud's phenomenon in patients with scleroderma". Am J Dig Dis. 21 (8): 601–6. PMID 952273.

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