Dalrymple sign

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Dalrymple sign is widened palpebral (eyelid) tissue or lid spasm seen in thyrotoxicosis (Graves' disease), causing abnormal wideness of the palpebral fissure. Retraction of the upper eyelid, the white of the sclera is visible at the upper margin of the cornea in direct outward stare. Pathognomonic eye symptom in Graves' disease. Other signs described within the symptomology of Graves' disease are Stellwag's sign (rare blinking), Rosenbach's sign (tremor of the eyelids), Jelink's sign (hyperpigmentation of the eyelid).

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