DNA sequence

Jump to navigation Jump to search
Electropherogram printout from automated sequencer showing part of a DNA sequence

WikiDoc Resources for DNA sequence

Articles

Most recent articles on DNA sequence

Most cited articles on DNA sequence

Review articles on DNA sequence

Articles on DNA sequence in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on DNA sequence

Images of DNA sequence

Photos of DNA sequence

Podcasts & MP3s on DNA sequence

Videos on DNA sequence

Evidence Based Medicine

Cochrane Collaboration on DNA sequence

Bandolier on DNA sequence

TRIP on DNA sequence

Clinical Trials

Ongoing Trials on DNA sequence at Clinical Trials.gov

Trial results on DNA sequence

Clinical Trials on DNA sequence at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on DNA sequence

NICE Guidance on DNA sequence

NHS PRODIGY Guidance

FDA on DNA sequence

CDC on DNA sequence

Books

Books on DNA sequence

News

DNA sequence in the news

Be alerted to news on DNA sequence

News trends on DNA sequence

Commentary

Blogs on DNA sequence

Definitions

Definitions of DNA sequence

Patient Resources / Community

Patient resources on DNA sequence

Discussion groups on DNA sequence

Patient Handouts on DNA sequence

Directions to Hospitals Treating DNA sequence

Risk calculators and risk factors for DNA sequence

Healthcare Provider Resources

Symptoms of DNA sequence

Causes & Risk Factors for DNA sequence

Diagnostic studies for DNA sequence

Treatment of DNA sequence

Continuing Medical Education (CME)

CME Programs on DNA sequence

International

DNA sequence en Espanol

DNA sequence en Francais

Business

DNA sequence in the Marketplace

Patents on DNA sequence

Experimental / Informatics

List of terms related to DNA sequence

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information.

The possible letters are A, C, G, and T, representing the four nucleotide subunits of a DNA strand - adenine, cytosine, guanine, thymine bases covalently linked to phospho-backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, going from 5' to 3' from left to right. A succession of any number of nucleotides greater than four is liable to be called a sequence. With regard to its biological function, which may depend on context, a sequence may be sense or anti-sense, and either coding or noncoding. DNA sequences can also contain "junk DNA."

Sequences can be derived from the biological raw material through a process called DNA sequencing.

In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:

       A = adenine           
       C = cytosine            
       G = guanine             
       T = thymine           
       R = G A (purine)        
       Y = T C (pyrimidine)    
       K = G T (keto)    
       M = A C (amino)
       S = G C (strong bonds)
       W = A T (weak bonds)
       B = G T C (all but A)
       D = G A T (all but C)
       H = A C T (all but G)
       V = G C A (all but T)
       N = A G C T (any)

See also

External links


bg:ДНК секвенция cs:Sekvence DNA de:Nukleotidsequenz ko:염기서열 id:Sekuens DNA th:ลำดับดีเอ็นเอ


Template:WikiDoc Sources