Cycloplegia

(Redirected from Cycloplegic)
Jump to navigation Jump to search
Cycloplegia
File:Cyclopentolate 1 percent Pupils.jpg
Dilated pupil (mydriasis) caused by Cyclopentolate 1% instilled into both eyes
ICD-10 H52.5
ICD-9 367.51
DiseasesDB 17379

WikiDoc Resources for Cycloplegia

Articles

Most recent articles on Cycloplegia

Most cited articles on Cycloplegia

Review articles on Cycloplegia

Articles on Cycloplegia in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Cycloplegia

Images of Cycloplegia

Photos of Cycloplegia

Podcasts & MP3s on Cycloplegia

Videos on Cycloplegia

Evidence Based Medicine

Cochrane Collaboration on Cycloplegia

Bandolier on Cycloplegia

TRIP on Cycloplegia

Clinical Trials

Ongoing Trials on Cycloplegia at Clinical Trials.gov

Trial results on Cycloplegia

Clinical Trials on Cycloplegia at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Cycloplegia

NICE Guidance on Cycloplegia

NHS PRODIGY Guidance

FDA on Cycloplegia

CDC on Cycloplegia

Books

Books on Cycloplegia

News

Cycloplegia in the news

Be alerted to news on Cycloplegia

News trends on Cycloplegia

Commentary

Blogs on Cycloplegia

Definitions

Definitions of Cycloplegia

Patient Resources / Community

Patient resources on Cycloplegia

Discussion groups on Cycloplegia

Patient Handouts on Cycloplegia

Directions to Hospitals Treating Cycloplegia

Risk calculators and risk factors for Cycloplegia

Healthcare Provider Resources

Symptoms of Cycloplegia

Causes & Risk Factors for Cycloplegia

Diagnostic studies for Cycloplegia

Treatment of Cycloplegia

Continuing Medical Education (CME)

CME Programs on Cycloplegia

International

Cycloplegia en Espanol

Cycloplegia en Francais

Business

Cycloplegia in the Marketplace

Patents on Cycloplegia

Experimental / Informatics

List of terms related to Cycloplegia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation.[1] Because of the paralysis of the ciliary muscle, the curvature of the lens can no longer be adjusted to focus on nearby objects. This results in similar problems as those caused by presbyopia, in which the lens has lost elasticity and can also no longer focus on close-by objects. Cycloplegia with accompanying mydriasis (dilation of pupil) is usually due to topical application of muscarinic antagonists such as atropine and cyclopentolate.

Anatomy

The iris is the heavily pigmented colored part of the eye. It has a contractile diaphragm in front of the lens with a central opening called the pupil. It is located between the lens and the cornea, and is attached radially to the ciliary body and the cornea via ligaments called pectinate ligaments.

The iris contains two sets of muscles:

The muscles regulate the amount of light entering the eye. The sphincter pupillae is stimulated through muscarinic receptors by the parasympathetic nervous system. The dilator pupillae is stimulated through noradrenergic receptors by the sympathetic nervous system.

Cycloplegic drugs

Cycloplegic drugs are generally muscarinic receptor blockers. These include atropine, cyclopentolate, homatropine, scopolamine and tropicamide. They are indicated for use in cycloplegic refraction (to paralyze the ciliary muscle in order to determine the true refractive error of the eye) and the treatment of uveitis. All cycloplegics are also mydriatic (pupil dilating) agents and are used as such during eye examination to better visualize the retina.

When cycloplegic drugs are used as a mydriatic to dilate the pupil, the pupil in the normal eye regains its function when the drugs are metabolized or carried away. Some cycloplegic drugs can cause dilation of the pupil for several days. Usually the ones used by ophthalmologists or optometrists wear off in hours, but when the patient leaves the office strong sunglasses are provided for comfort.

See also

References

Template:Mydriatics and cycloplegics