Curling's ulcer

(Redirected from Curling ulcers)
Jump to navigation Jump to search

WikiDoc Resources for Curling's ulcer

Articles

Most recent articles on Curling's ulcer

Most cited articles on Curling's ulcer

Review articles on Curling's ulcer

Articles on Curling's ulcer in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Curling's ulcer

Images of Curling's ulcer

Photos of Curling's ulcer

Podcasts & MP3s on Curling's ulcer

Videos on Curling's ulcer

Evidence Based Medicine

Cochrane Collaboration on Curling's ulcer

Bandolier on Curling's ulcer

TRIP on Curling's ulcer

Clinical Trials

Ongoing Trials on Curling's ulcer at Clinical Trials.gov

Trial results on Curling's ulcer

Clinical Trials on Curling's ulcer at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Curling's ulcer

NICE Guidance on Curling's ulcer

NHS PRODIGY Guidance

FDA on Curling's ulcer

CDC on Curling's ulcer

Books

Books on Curling's ulcer

News

Curling's ulcer in the news

Be alerted to news on Curling's ulcer

News trends on Curling's ulcer

Commentary

Blogs on Curling's ulcer

Definitions

Definitions of Curling's ulcer

Patient Resources / Community

Patient resources on Curling's ulcer

Discussion groups on Curling's ulcer

Patient Handouts on Curling's ulcer

Directions to Hospitals Treating Curling's ulcer

Risk calculators and risk factors for Curling's ulcer

Healthcare Provider Resources

Symptoms of Curling's ulcer

Causes & Risk Factors for Curling's ulcer

Diagnostic studies for Curling's ulcer

Treatment of Curling's ulcer

Continuing Medical Education (CME)

CME Programs on Curling's ulcer

International

Curling's ulcer en Espanol

Curling's ulcer en Francais

Business

Curling's ulcer in the Marketplace

Patents on Curling's ulcer

Experimental / Informatics

List of terms related to Curling's ulcer


Curling's ulcer is an acute peptic ulcer of the duodenum resulting as a complication from severe burns when reduced plasma volume leads to sloughing of the gastric mucosa. The condition was first described in 1823 and named for a doctor, Thomas Blizard Curling, who observed ten such patients in 1842.[1]

These stress ulcers were once a common complication of serious burns, presenting in over 10% of cases,[1] and especially common in child burn victims.[2] They result in perforation and hemorrhage more often than other forms of intestinal ulceration[3] and had correspondingly high mortality rates.[1] While emergency surgery was once the only treatment, combination therapies including enteral feeding with powerful antacids such as H2-receptor antagonists or, more recently, proton pump inhibitors such as omeprazole have made Curling's ulcer a rare complication.[4]

A similar condition involving elevated intracranial pressure is known as Cushing ulcer.

References

  1. 1.0 1.1 1.2 Pruitt, Basil A., Jr., F.D. Foley and John A. Moncrief (Oct 1970). "Curling's Ulcer:A Clinical-Pathology Study of 323 Cases". Annals of Surgery. 172.
  2. Bruck, H.M. and Basil A. Pruitt, Jr. (Jun 1972). "Curling's ulcer in children: a 12-year review of 63 cases". Journal of Trauma. 12.
  3. Lev, Robert; et al. (Dec 1973). "Stress erosions". Digestive Diseases and Sciences. 18.
  4. Moran, K.T., T. O'Reilly and A.M. Munster (Oct 1987). "A combined regimen for the prophylaxis of Curling's ulcer". American Surgeons. 53.


Template:WH Template:WS