Chromophobe

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Chromophobe

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The term chromophobe refers to histological structures which do not take up colored dye readily, and thus appear more relatively pale under the microscope -- hence their "fear" ("phobia") of "color" ("chrome").

Pituitary

The term is most commonly associated with the anterior pituitary, where approximately half of the cells are considered chromophobes. (Of the remaining cells, about a third are basophils, and the other two thirds acidophils.) The chromophobe cells do not actually appear clear, but rather a light blue (in contrast to the deep blue of the basophils.)[1]

Cancer

"Chromophobe" also refers to a type of renal cell carcinoma (distinct from "clear cell").[2]

References

  1. Histology at Boston University 14002loa
  2. http://www.cancer.org/docroot/cri/content/cri_2_4_1x_what_is_kidney_cancer_22.asp

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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