Chloramine-T

Jump to navigation Jump to search

Template:Chembox new

WikiDoc Resources for Chloramine-T

Articles

Most recent articles on Chloramine-T

Most cited articles on Chloramine-T

Review articles on Chloramine-T

Articles on Chloramine-T in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Chloramine-T

Images of Chloramine-T

Photos of Chloramine-T

Podcasts & MP3s on Chloramine-T

Videos on Chloramine-T

Evidence Based Medicine

Cochrane Collaboration on Chloramine-T

Bandolier on Chloramine-T

TRIP on Chloramine-T

Clinical Trials

Ongoing Trials on Chloramine-T at Clinical Trials.gov

Trial results on Chloramine-T

Clinical Trials on Chloramine-T at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Chloramine-T

NICE Guidance on Chloramine-T

NHS PRODIGY Guidance

FDA on Chloramine-T

CDC on Chloramine-T

Books

Books on Chloramine-T

News

Chloramine-T in the news

Be alerted to news on Chloramine-T

News trends on Chloramine-T

Commentary

Blogs on Chloramine-T

Definitions

Definitions of Chloramine-T

Patient Resources / Community

Patient resources on Chloramine-T

Discussion groups on Chloramine-T

Patient Handouts on Chloramine-T

Directions to Hospitals Treating Chloramine-T

Risk calculators and risk factors for Chloramine-T

Healthcare Provider Resources

Symptoms of Chloramine-T

Causes & Risk Factors for Chloramine-T

Diagnostic studies for Chloramine-T

Treatment of Chloramine-T

Continuing Medical Education (CME)

CME Programs on Chloramine-T

International

Chloramine-T en Espanol

Chloramine-T en Francais

Business

Chloramine-T in the Marketplace

Patents on Chloramine-T

Experimental / Informatics

List of terms related to Chloramine-T


N-chloro tosylamide sodium salt, sold as chloramine-T, is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant. It is a white powder that gives unstable solutions with water.

Chemistry

As a N-chloro compound, it contains active (electrophilic) chlorine and can be compared to the O-chlorinated sodium hypochlorite. Chloramine-T is nearly neutral (pH typically 8.5). In water, it breaks down to the disinfectant hypochlorite. It can be used as a source of electrophilic chlorine in organic synthesis.

The sulfur adjacent to the nitrogen can stabilize a nitrogen anion (R2N), so that the N-chloro sulfonyamide moiety can be deprotonated at nitrogen even with only sodium hydroxide.

Use as a biocide

Chloramine-T is used for disinfection and as an algicide, bactericide, germicide, for parasite control, and for drinking water disinfection. The molecular structure of toluenesulfonylamide is similar to para-aminobenzoic acid, an intermediate in bacterial metabolism, which is disrupted by this sulfonamide (in the same way as by a sulfa drug). Therefore, chloramine-T is capable of inhibiting with bacterial growth with two mechanisms, with the phenylsulfonamide moiety and the electrophilic chlorine.

External links

nl:Chloramine-T

Template:WS