Cathepsin W

Jump to: navigation, search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cathepsin W is a protein that in humans is encoded by the CTSW gene.[1][2][3]

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2.[3]

References

  1. Linnevers C, Smeekens SP, Bromme D (May 1997). "Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes". FEBS Lett. 405 (3): 253–9. doi:10.1016/S0014-5793(97)00118-X. PMID 9108299.
  2. Wex T, Levy B, Smeekens SP, Ansorge S, Desnick RJ, Bromme D (Aug 1998). "Genomic structure, chromosomal localization, and expression of human cathepsin W". Biochem Biophys Res Commun. 248 (2): 255–61. doi:10.1006/bbrc.1998.8954. PMID 9675123.
  3. 3.0 3.1 "Entrez Gene: CTSW cathepsin W".

Further reading

External links

  • The MEROPS online database for peptidases and their inhibitors: C01.037



Linked-in.jpg