Carbarsone

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Carbarsone
File:NIH CARBARSONE.png
Clinical data
Pregnancy
category
  • ?
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • ?
Pharmacokinetic data
Bioavailability?
Metabolism?
Elimination half-life?
Excretion?
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC7H9AsN2O4
Molar mass260.079 g/mol

Carbarsone is an arsenic-based antiprotozoal drug which has been used in the treatment of amebiasis and other infections.[1][2][3] It was available for use in the United States as a drug for amebiasis as late as 1991. Thereafter, it remained available as an additive for turkey feed for improving weight and controlling Blackhead disease.[4][5]

References

  1. SASAKI T, YOKAGAWA M, WYKOFF DE, RITICHIE LS (1956). "Asymptomatic amebiasis; treatment with atabrine in combination with carbarsone or chiniofon". United States Armed Forces medical journal. 7 (3): 363–8. PMID 13299463.
  2. RADKE RA (1955). "Ameboma of the intestine: an analysis of the disease as presented in 78 collected and 41 previously unreported cases". Ann. Intern. Med. 43 (5): 1048–66. PMID 13268997.
  3. HOEKENGA MT (1951). "A comparison of aureomycin and carbarsone in the treatment of intestinal amebiasis". Am. J. Trop. Med. Hyg. 31 (4): 423–5. PMID 14857246.
  4. McDougald LR (1979). "Efficacy and compatibility of amprolium and carbarsone against Coccidiosis and blackhead in turkeys". Poult. Sci. 58 (1): 76–80. PMID 572970.
  5. Worden AN, Wood EC (1973). "The effect of Carbarsone (33.6 per cent w-v p-ureidobenzene arsonic acid) on bodyweight gain, food conversion and tissue arsenic levels of turkey poults". J. Sci. Food Agric. 24 (1): 35–41. PMID 4696593.