COG8

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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Conserved oligomeric Golgi complex subunit 8 is a protein that in humans is encoded by the COG8 gene.[1][2]

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi complex (COG), which includes COG8 (Ungar et al., 2002).[supplied by OMIM][2]

References

  1. Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function". J Cell Biol. 157 (3): 405–15. doi:10.1083/jcb.200202016. PMC 2173297. PMID 11980916.
  2. 2.0 2.1 "Entrez Gene: COG8 component of oligomeric golgi complex 8".

Further reading

External links