CA10

For the Federal Circuit Court of Appeals, see United States Court of Appeals for the Tenth Circuit. For the highway, see California State Route 10. For the congressional district, see California's 10th congressional district.

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External IDs	GeneCards: [1]
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Species	Human	Mouse
Entrez	n/a	n/a
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RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
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Wikidata
View/Edit Human

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.

This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.

External links

• Human CA10 genome location and CA10 gene details page in the UCSC Genome Browser.

Further reading

• Supuran CT, Scozzafava A, Casini A (2003). "Carbonic anhydrase inhibitors". Med Res Rev. 23 (2): 146–89. doi:10.1002/med.10025. PMID 12500287.
• Supuran CT, Vullo D, Manole G, et al. (2005). "Designing of novel carbonic anhydrase inhibitors and activators". Curr Med Chem Cardiovasc Hematol Agents. 2 (1): 49–68. doi:10.2174/1568016043477305. PMID 15328829.
• Pastorekova S, Parkkila S, Pastorek J, Supuran CT (2004). "Carbonic anhydrases: current state of the art, therapeutic applications and future prospects". J Enzyme Inhib Med Chem. 19 (3): 199–229. doi:10.1080/14756360410001689540. PMID 15499993.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Okamoto N, Fujikawa-Adachi K, Nishimori I, et al. (2001). "cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain". Biochim. Biophys. Acta. 1518 (3): 311–6. doi:10.1016/s0167-4781(01)00193-2. PMID 11311946.
• Taniuchi K, Nishimori I, Takeuchi T, et al. (2002). "Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain". Neuroscience. 112 (1): 93–9. doi:10.1016/S0306-4522(02)00066-0. PMID 12044474.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.