Bromobimane

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Template:Chembox E numberTemplate:Chembox SolubilityInWater
Bromobimane
Other names Bromobimane, mBBr
Identifiers
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Properties
C10H11BrN2O2
Molar mass 271.11
Melting point
Hazards
Main hazards alkylating agent
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Bromobimane is a heterocyclic compound that is used as a reagent in biochemistry. It alkylates thiol groups, replacing the H with a fluorescent tag (λemission = 478 nm). Its alkylating properties are comparable to iodoacetamide.[1]

References

  1. Paul C. Chinn, Vincent Pigiet, and Robert C. Fahey (1986). "Determination of thiol proteins using monobromobimane labeling and high-performance liquid chromatographic analysis: Application to Escherichia coli thioredoxin". Analytical Biochemistry. 159: 143–149. doi:10.1016/0003-2697(86)90319-2.

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