Bifonazole

	WikiDoc Resources for Bifonazole
Articles
Most recent articles on Bifonazole Most cited articles on Bifonazole Review articles on Bifonazole Articles on Bifonazole in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Bifonazole Images of Bifonazole Photos of Bifonazole Podcasts & MP3s on Bifonazole Videos on Bifonazole
Evidence Based Medicine
Cochrane Collaboration on Bifonazole Bandolier on Bifonazole TRIP on Bifonazole
Clinical Trials
Ongoing Trials on Bifonazole at Clinical Trials.gov Trial results on Bifonazole Clinical Trials on Bifonazole at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Bifonazole NICE Guidance on Bifonazole NHS PRODIGY Guidance FDA on Bifonazole CDC on Bifonazole
Books
Books on Bifonazole
News
Bifonazole in the news Be alerted to news on Bifonazole News trends on Bifonazole
Commentary
Blogs on Bifonazole
Definitions
Definitions of Bifonazole
Patient Resources / Community
Patient resources on Bifonazole Discussion groups on Bifonazole Patient Handouts on Bifonazole Directions to Hospitals Treating Bifonazole Risk calculators and risk factors for Bifonazole
Healthcare Provider Resources
Symptoms of Bifonazole Causes & Risk Factors for Bifonazole Diagnostic studies for Bifonazole Treatment of Bifonazole
Continuing Medical Education (CME)
CME Programs on Bifonazole
International
Bifonazole en Espanol Bifonazole en Francais
Business
Bifonazole in the Marketplace Patents on Bifonazole
Experimental / Informatics
List of terms related to Bifonazole

Bifonazole
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	topic
ATC code	D01AC10 (WHO) ;
Legal status
Legal status	US: OTC ;
Identifiers
	IUPAC name (RS)-1-[Phenyl(4-phenylphenyl)methyl]-1H-imidazole;
CAS Number	60628-96-8 ;
PubChem CID	2378;
DrugBank	DB04794 ;
ChemSpider	2287 ;
UNII	QYJ305Z91O;
KEGG	D01775 ;
ChEBI	CHEBI:31286 ;
ChEMBL	ChEMBL277535 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C22H18N2
Molar mass	310.392 g/mol
3D model (JSmol)	Interactive image;
	SMILES n1ccn(c1)C(c3ccc(c2ccccc2)cc3)c4ccccc4;
	InChI InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H ; Key:OCAPBUJLXMYKEJ-UHFFFAOYSA-N ;
(what is this?) (verify)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.

Bifonazole has dual mode of action. It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungi together with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs.

v t e Antifungals (D01 and J02)
Antibiotics	Griseofulvin • polyene antimycotics (Natamycin, Nystatin)
Topical azoles	imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole)
Other topicals	Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine)
For systemic use	Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin)
Other	Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	topic
ATC code	D01AC10 (WHO)
Legal status
Legal status	US: OTC
Identifiers
IUPAC name (RS)-1-[Phenyl(4-phenylphenyl)methyl]-1H-imidazole
CAS Number	60628-96-8^Y
PubChem CID	2378
DrugBank	DB04794^Y
ChemSpider	2287^Y
UNII	QYJ305Z91O
KEGG	D01775^Y
ChEBI	CHEBI:31286^N
ChEMBL	ChEMBL277535^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₂H₁₈N₂
Molar mass	310.392 g/mol
3D model (JSmol)	Interactive image
SMILES n1ccn(c1)C(c3ccc(c2ccccc2)cc3)c4ccccc4
InChI InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H^Y Key:OCAPBUJLXMYKEJ-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)