Beriberi diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]
Overview
Monitoring the patient's response after thiamine administration is the most cost-effective diagnostic study. A positive response is recorded if the patients clinical condition or cardiac function improved following thiamine administration.
Diagnostic Study of Choice
Study of Choice
Thiamine replacement test
- To administer thiamine to the patient and monitor the patient's response.
- This test is easy, safe (as thiamine is not toxic in high doses), and saves time, efforts, and cost into the patient's treatment.[1]
Diagnostic results
The following finding on performing thiamine replacement test is confirmatory for beriberi:
- Clinical improvement of the patient's symptoms
- Echocardiographic improvement of cardiac function.
References
- ↑ Edwards KA, Tu-Maung N, Cheng K, Wang B, Baeumner AJ, Kraft CE (2017). "Thiamine Assays-Advances, Challenges, and Caveats". ChemistryOpen. 6 (2): 178–191. doi:10.1002/open.201600160. PMC 5390807. PMID 28413748.