Benzthiazide
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| Image:Benzthiazide.svg | |
| Benzthiazide
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| Systematic (IUPAC) name | |
| 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)- 4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C15H14ClN3O4S3 |
| Mol. mass | 430.983 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 60 to 70% |
| Protein binding | 30% |
| Metabolism | ? |
| Half life | 5 to 15 hours |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
℞ Prescription only |
| Routes | Oral |
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Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others[1]) is a thiazide diuretic used in the treatment of high blood pressure and edema. It is no longer available in the United States.
In the United Kingdom, it was also sold in combination with the potassium-sparing diuretic triamterene under the trade name Dytide.[2] The same combination is still available in Switzerland as Dyrenium compositum.[3]
References
- ↑ David J. Triggle; C. R. Ganellin, F. MacDonald (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC, p. 246. ISBN 0-412-46630-9. Retrieved on August 29, 2008 through Google Book Search.
- ↑ Triamterene and Benzthiazide. PatientUK (2005). Retrieved on 2008-08-29.
- ↑ Dyrenium® compositum. Doetsch Grether (n.d.). Retrieved on 2008-08-29.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
