Normoblast

Normoblast
Bone Marrow: Multilobulated Normoblast. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

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List of terms related to Normoblast

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

An erythroblast is a type of red blood cell which still retains a cell nucleus. It is the immediate precursor of a normal erythrocyte.

Nomenclature

The term normoblast is sometimes used as a synonym for erythroblast, but at other times it is considered a subcategory. In the latter context, there are two types of erythroblasts:

• "normoblasts" - develop as expected
• "megaloblasts" - an unusually large erythroblast that can be associated with pernicious anemia and folic acid deficiency (collectively called megaloblastic anemia)

Development

There are four stages in the development of a normoblast.

Image	Description
	Pronormoblast
	Basophilic normoblast
	Polychromatic normoblast (also polychromatophilic)
	Orthochromatic normoblast (also orthochromatophilic)

Additional images

• 
  Blood cell lineage
• 
  Hematopoiesis
• 
  Blood: Schistocytes: Micro blood film shows an excellent example with normoblast.

See also

• Erythropoiesis
• Hemopoiesis
• Pluripotential hemopoietic stem cell

External links

• Pronormoblasts Presented by the University of Virginia
• Basophilic Normoblasts Presented by the University of Virginia
• Polychromatophilic Normoblasts Presented by the University of Virginia
• Orthochromatic Normoblasts Presented by the University of Virginia
• Template:Dorlands - "normoblast"
• Template:Dorlands - "erythroblast"
• Template:EMedicineDictionary
• Normoblasts at the US National Library of Medicine Medical Subject Headings (MeSH)
• Histology image: 01804loa – Histology Learning System at Boston University - "Bone Marrow and Hemopoiesis bone marrow smear, erythroblast series with proerythroblast "
• Histology at uiowa.edu

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