Atrial fibrillation epidemiology

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Conduction
Sinus rhythm
Atrial fibrillation
Atrial fibrillation
Classification and external resources
The P waves, which represent depolarization of the atria, are irregular or absent during atrial fibrillation.
ICD-10 I48.
ICD-9 427.31
DiseasesDB 1065
MedlinePlus 000184
eMedicine med/184  emerg/46

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Synonyms and related keywords: AF, Afib, fib

Epidemiology

Atrial fibrillation is the most common arrhythmia found in clinical practice.[1] It also accounts for 1/3 of hospital admissions for cardiac rhythm disturbances[1], and the rate of admissions for AF has risen in recent years.[2] Approximately 2.2 million individuals in the United States and 4.5 million in the European Union have AF.[1][3]

The incidence of atrial fibrillation increases with age. The prevalence in individuals over the age of 80 is about 8%.[4] In developed countries, the number of patients with atrial fibrillation is likely to increase during the next 50 years, due to the growing proportion of elderly individuals.[5]

Prevalence

It should be noted that the prevalence of atrial fibrillation increases with increasing age, and its prevalence is increased among Caucasians, patients with hypertension and valvular heart disease[6]. The prevalence in the general population is 0.4%.[7]

Important genetic determinants may play a role in so far as the age-adjusted risk of developing atrial fibrillation among African-Americans is less than half that in Caucasians. [8][9] [10] The presence of atrial fibrillation often reflects the presence of underlying cardiac or lung disease. Indeed, the proportion of patients with “lone” atrial fibrillation, (that is those patients with atrial fibrillation in whom there is no cardiac or lung disease history) is low at about 12% of cases. [11][10][12][13] Patients with atrial fibrillation tend to be older with a median age of 75 years. The proportion of patients with atrial fibrillation who are between 65 and 85 years of age is 70%, and females predominate in the very elderly (60% of atrial fibrillation patients over the age of 75 are women).[14] Despite the fact that there are more very elderly women with atrial fibrillation, when age is adjusted for, the prevalence of atrial fibrillation is higher in men.[10][15] The rate of rise per year in the risk of atrial fibrillation is slightly higher in the very elderly (1.5% per year for women and 2.0% per year for men over the age of 80 years). These rates are nearly 15 to 20 times higher than in those under the age of 40.[16][17][18]

See Also

References

  1. Cite error 8; No text given.
  2. Friberg J, Buch P, Scharling H, Gadsbphioll N, Jensen GB. (2003). "Rising rates of hospital admissions for atrial fibrillation". Epidemiology 14 (6): 666–72. doi:10.1097/01.ede.0000091649.26364.c0. PMID 14569181.
  3. Go AS, Hylek EM, Phillips KA, et al (2001). "Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study". JAMA 285 (18): 2370–5. doi:10.1001/jama.285.18.2370. PMID 11343485.
  4. Furberg CD, Psaty BM, Manolio TA, Gardin JM, Smith VE, Rautaharju PM (1994). "Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study)". Am. J. Cardiol. 74 (3): 236–41. doi:10.1016/0002-9149(94)90363-8. PMID 8037127.
  5. Go AS, Hylek EM, Phillips KA, Chang Y, Henault LE, Selby JV, Singer DE (2001). "Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study". JAMA 285 (18): 2370–5. doi:10.1001/jama.285.18.2370. PMID 11343485. PMID 11343485
  6. Fuster V, Rydén LE, Asinger RW, et al (October 2001). "ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to develop guidelines for the management of patients with atrial fibrillation) developed in collaboration with the North American Society of Pacing and Electrophysiology". Eur. Heart J. 22 (20): 1852–923. doi:10.1053/euhj.2001.2983. PMID 11601835.
  7. OSTRANDER LD, BRANDT RL, KJELSBERG MO, EPSTEIN FH (June 1965). "ELECTROCARDIOGRAPHIC FINDINGS AMONG THE ADULT POPULATION OF A TOTAL NATURAL COMMUNITY, TECUMSEH, MICHIGAN". Circulation 31: 888–98. PMID 14297523.
  8. Flegel KM, Shipley MJ, Rose G (March 1987). "Risk of stroke in non-rheumatic atrial fibrillation". Lancet 1 (8532): 526–9.
  9. Wolf PA, Abbott RD, Kannel WB (August 1991). "Atrial fibrillation as an independent risk factor for stroke: the Framingham Study". Stroke 22 (8): 983–8. PMID 1866765.
  10. 10.0 10.1 10.2 Furberg CD, Psaty BM, Manolio TA, Gardin JM, Smith VE, Rautaharju PM (August 1994). "Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study)". Am. J. Cardiol. 74 (3): 236–41. PMID 8037127.
  11. Kopecky SL, Gersh BJ, McGoon MD, et al (September 1987). "The natural history of lone atrial fibrillation. A population-based study over three decades". N. Engl. J. Med. 317 (11): 669–74. PMID 3627174.
  12. EVANS W, SWANN P (April 1954). "Lone auricular fibrillation". Br Heart J 16 (2): 189–94. PMID 13160271.
  13. Brand FN, Abbott RD, Kannel WB, Wolf PA (December 1985). "Characteristics and prognosis of lone atrial fibrillation. 30-year follow-up in the Framingham Study". JAMA 254 (24): 3449–53. PMID 4068186.
  14. Feinberg WM, Blackshear JL, Laupacis A, Kronmal R, Hart RG (March 1995). "Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications". Arch. Intern. Med. 155 (5): 469–73. PMID 7864703.
  15. Kannel WB, Abbott RD, Savage DD, McNamara PM (August 1983). "Coronary heart disease and atrial fibrillation: the Framingham Study". Am. Heart J. 106 (2): 389–96. PMID 6869222.
  16. Psaty BM, Manolio TA, Kuller LH, et al (October 1997). "Incidence of and risk factors for atrial fibrillation in older adults". Circulation 96 (7): 2455–61. PMID 9337224.
  17. Wolf PA, Abbott RD, Kannel WB (September 1987). "Atrial fibrillation: a major contributor to stroke in the elderly. The Framingham Study". Arch. Intern. Med. 147 (9): 1561–4. PMID 3632164.
  18. Krahn AD, Manfreda J, Tate RB, Mathewson FA, Cuddy TE (May 1995). "The natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba Follow-Up Study". Am. J. Med. 98 (5): 476–84. doi:10.1016/S0002-9343(99)80348-9. PMID 7733127.

Further Readings

  • Fuster V, Rydén LE, Cannom DS, et al (2006). "ACC/AHA/ESC 2006 Guidelines for the Management of Patients with Atrial Fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society". Circulation 114 (7): e257-354. doi:10.1161/CIRCULATIONAHA.106.177292. PMID 16908781.
  • Estes NAM 3rd, Halperin JL, Calkins H, Ezekowitz MD, Gitman P, Go AS, McNamara RL, Messer JV, Ritchie JL, Romeo SJW, Waldo AL, Wyse DG. ACC/AHA/Physician Consortium 2008 clinical performance measures for adults with non valvular atrial fibrillation or atrial flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physician Consortium for Performance Improvement (Writing Committee to Develop Performance Measures for Atrial Fibrillation). Circulation 2008; 117:1101–1120
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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .