Atopic dermatitis primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shalinder Singh, M.B.B.S.[2]

Overview

Primary prevention applies to the patients with history of other atopic diseases and has not been diagnosed with atopic dermatits yet. Its primary goal is to reduce the risk of developing atopic dermatitis in the future.

Primary Prevention

Approaches to reduce development of atopic dermatitis in children includes:

  • Infections
    • Children who are frequently exposed to infections, carry an increased probability of development of atopic dermatitis and other allergic diseases.[1]
    • Administration of probiotic bacteria in pregnant women 2–4 weeks before delivery and in infants for 6 months after birth.[2]
    • Minimization of infections in infants.
  • Vaccination
    • Contrary to old studies, recent published studies has observed a significantly lower risk of asthma and atopic diseases in children vaccinated vs children who were not vaccinated.[3]
  • Milk
  • Animals
    • Possession of fur animals in the house has significant affect on reduction of development of atopic dermatitis in children.[5]
  • Breastfeeding
    • Breastfeeding 4 months or more decreases the risk of development of atopic dermatitis and other atopic diseases upto 4 years of age.[6]
    • Exclusive breastfeeding in the first 4–6 months of age.
  • Avoiding renovated houses during pregnancy.

References

  1. McKeever TM, Lewis SA, Smith C, Collins J, Heatlie H, Frischer M, Hubbard R (January 2002). "Early exposure to infections and antibiotics and the incidence of allergic disease: a birth cohort study with the West Midlands General Practice Research Database". J. Allergy Clin. Immunol. 109 (1): 43–50. PMID 11799364.
  2. Kalliomäki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E (April 2001). "Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial". Lancet. 357 (9262): 1076–9. doi:10.1016/S0140-6736(00)04259-8. PMID 11297958.
  3. Martignon G, Oryszczyn MP, Annesi-Maesano I (May 2005). "Does childhood immunization against infectious diseases protect from the development of atopic disease?". Pediatr Allergy Immunol. 16 (3): 193–200. doi:10.1111/j.1399-3038.2005.00254.x. PMID 15853947.
  4. Perkin MR, Strachan DP (June 2006). "Which aspects of the farming lifestyle explain the inverse association with childhood allergy?". J. Allergy Clin. Immunol. 117 (6): 1374–81. doi:10.1016/j.jaci.2006.03.008. PMID 16751000.
  5. Halken S, Høst A, Hansen LG, Osterballe O (October 1992). "Effect of an allergy prevention programme on incidence of atopic symptoms in infancy. A prospective study of 159 "high-risk" infants". Allergy. 47 (5): 545–53. PMID 1485660.
  6. Kull I, Böhme M, Wahlgren CF, Nordvall L, Pershagen G, Wickman M (September 2005). "Breast-feeding reduces the risk for childhood eczema". J. Allergy Clin. Immunol. 116 (3): 657–61. doi:10.1016/j.jaci.2005.04.028. PMID 16159639.

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