Aspergillus nidulans
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| Aspergillus nidulans | ||||||||||||||
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| Scientific classification | ||||||||||||||
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| Binomial name | ||||||||||||||
| Aspergillus nidulans G Winter 1884 | ||||||||||||||
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Emericella nidulans |
Aspergillus nidulans (also called Emericella nidulans) is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology [1] for over 50 years, [2] being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, pathogenesis, and metabolism.[3] It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner.
Genome
The genome of A. nidulans, sequenced at the Broad Institute, was published in December 2005. [4] It is 30 million base pairs in size and is predicted to contain around 9,500 protein-coding genes on eight chromosomes.
References
- ↑ Osmani SA, Mirabito PM (2004). "The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans". Fungal Genet Biol 41 (4): 401-10. PMID 14998523.
- ↑ Martinelli, S. D.; J. R. Kinghorn (1994). Aspergillus: 50 years on. Elsevier. ISBN 0-444-81762-X.
- ↑ Nierman WC, May G, Kim HS, Anderson MJ, Chen D, Denning DW (2005). "What the Aspergillus genomes have told us". Med Mycol 43 Suppl 1: S3-5. PMID 16110785.
- ↑ Galagan JE et al (2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature 438 (7071): 1105-15. PMID 16372000.
External links
- Aspergillus nidulans genome [1]
- Fungal Genetics Stock Center
Major model organisms in genetics |
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| Sheep · Lambda phage · E. coli · Chlamydomonas · Tetrahymena · Budding yeast · Fission yeast · Neurospora · Maize · Arabidopsis · Medicago truncatula · C. elegans · Drosophila · Xenopus · Zebrafish · Rat · Mouse |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
