Aschoff body
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Aschoff bodies or Aschoff nodules are painless nodules present in rheumatic fever. Fully developed Aschoff bodies consist of fibrinoid change in connective tissue, lymphocytes, occasional plasma cells, and abnormal characteristic histiocytes. They are Aschoff cell granulomas with a fibrinoid necrotic centre found in the myocardium surrounding blood vessels, and other regions of the body. Myocytes in the myocardium can merge with the Aschoff cells to form giant cells of Aschoff. In addition, there are leukocytes, lymphocytes, eosinophils and plasma cells. The Aschoff bodies were discovered by the German pathologist Ludwig Aschoff.
Image link: http://erl.pathology.iupui.edu/C603/GENE426.HTM
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
