- N-formyl-L-kynurenine + H2O formate + L-kynurenine
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is aryl-formylamine amidohydrolase. Other names in common use include kynurenine formamidase, formylase, formylkynureninase, formylkynurenine formamidase, formamidase I, and formamidase II. This enzyme participates in tryptophan metabolism and glyoxylate and dicarboxylate metabolism.
- IUBMB entry for 22.214.171.124
- BRENDA references for 126.96.36.199 (Recommended.)
- PubMed references for 188.8.131.52
- PubMed Central references for 184.108.40.206
- Google Scholar references for 220.127.116.11
- HAYAISHI O, STANIER RY (1951). "The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway". J. Bacteriol. 62: 691&ndash, 709. PMID 14907621.
- JAKOBY WB (1954). "Kynurenine formamidase from Neurospora". J. Biol. Chem. 207: 657&ndash, 63. PMID 13163050.
- MEHLER AH, KNOX WE (1950). "The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine". J. Biol. Chem. 187: 431&ndash, 8. PMID 14794728.
- The CAS registry number for this enzyme class is 156229-75-3.
Gene Ontology (GO) codes
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