Aryl-aldehyde dehydrogenase

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In enzymology, an aryl-aldehyde dehydrogenase (EC 1.2.1.29) is an enzyme that catalyzes the chemical reaction

an aromatic aldehyde + NAD+ + H2O an aromatic acid + NADH + H+

The 3 substrates of this enzyme are aromatic aldehyde, NAD+, and H2O, whereas its 3 products are aromatic acid, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is aryl-aldehyde:NAD+ oxidoreductase. This enzyme participates in tyrosine metabolism and biphenyl degradation.

References

  • IUBMB entry for 1.2.1.29
  • BRENDA references for 1.2.1.29 (Recommended.)
  • PubMed references for 1.2.1.29
  • PubMed Central references for 1.2.1.29
  • Google Scholar references for 1.2.1.29
  • Raison JK, Henson G, Rienits KG (1966). "The oxidation of gentisaldehyde by nicotinamide-adenine dinucleotide-specific, aromatic aldehyde dehydrogenase from rabbit liver". Biochim. Biophys. Acta. 118: 285&ndash, 98. PMID 4289834.

External links

The CAS registry number for this enzyme class is 37250-94-5.

Gene Ontology (GO) codes

Template:1.2-enzyme-stub


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