Anti-actin antibodies
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Anti-actin antibodies. Anti-actin antibodies are found at increased frequency in certain autoimmune diseases and may be of some diagnostic value.
In coeliac disease anti-actin antibodies correlated with the level of intestinal damage. [1][2]
In autoimmune hepatitis anti-actin antibodies correlate with patterns of immune recognition[3], the pattern of recognition was specific to a small percentage of auto-immune hepatitis type 1 or cryptogenic hepatitis patients.[4]
in gastric cancer anti-actin antibodies were elevated, along with other antibodies in severe disease with poor outcomes.[5]
References
- ↑ Pedreira S, Sugai E, Moreno ML, et al (2005). "Significance of smooth muscle/anti-actin autoantibodies in celiac disease". Acta Gastroenterol. Latinoam. 35 (2): 83-93. PMID 16127984.
- ↑ Carroccio A, Brusca I, Iacono G, et al (2007). "IgA anti-actin antibodies ELISA in coeliac disease: A multicentre study". doi:10.1016/j.dld.2007.06.004. PMID 17652043.
- ↑ Muratori P, Muratori L, Agostinelli D, et al (2002). "Smooth muscle antibodies and type 1 autoimmune hepatitis". Autoimmunity 35 (8): 497-500. PMID 12765475.
- ↑ Ballot E, Homberg JC, Johanet C (2000). "Antibodies to soluble liver antigen: an additional marker in type 1 auto-immune hepatitis". J. Hepatol. 33 (2): 208-15. PMID 10952238.
- ↑ Konstandoulakis MM, Syrigos KN, Leandros M, Charalabopoulos A, Manouras A, Golematis BC (1998). "Autoantibodies in the serum of patients with gastric cancer: their prognostic importance". Hybridoma 17 (5): 431-5. PMID 9873988.
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
