Anthralin
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
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Overview
Anthralin is an antipsoriatic that is FDA approved for the treatment of chronic psoriasis. Common adverse reactions include hypersensitivity.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
- Topical treatment of chronic psoriasis
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Anthralin in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Anthralin in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Anthralin FDA-Labeled Indications and Dosage (Pediatric) in the drug label.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Anthralin in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Anthralin in pediatric patients.
Contraindications
There is limited information regarding Anthralin Contraindications in the drug label.
Warnings
- For external use only.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Anthralin Clinical Trials Experience in the drug label.
Postmarketing Experience
Drug Interactions
There is limited information regarding Anthralin Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Anthralin in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Anthralin in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Anthralin during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Anthralin in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Anthralin in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Anthralin in geriatric settings.
Gender
There is no FDA guidance on the use of Anthralin with respect to specific gender populations.
Race
There is no FDA guidance on the use of Anthralin with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Anthralin in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Anthralin in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Anthralin in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Anthralin in patients who are immunocompromised.
Administration and Monitoring
Administration
Monitoring
There is limited information regarding Anthralin Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Anthralin and IV administrations.
Overdosage
There is limited information regarding Anthralin overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
| |
| |
Anthralin
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| Systematic (IUPAC) name | |
| 1,8-dihydroxy-9,10-dihydroanthracen-9-one | |
| Identifiers | |
| CAS number | |
| ATC code | D05 |
| PubChem | |
| Chemical data | |
| Formula | Template:OrganicBox atomTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox |
| Mol. mass | 226.227 g/mol |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | 0%, trace amounts metabolites |
| Protein binding | 0% |
| Metabolism | absorbed and oxidised within the skin |
| Half life | n/a |
| Excretion | n/a |
| Therapeutic considerations | |
| Pregnancy cat. |
B2(AU) |
| Legal status |
P(UK) |
| Routes | topical |
Mechanism of Action
There is limited information regarding Anthralin Mechanism of Action in the drug label.
Structure
There is limited information regarding Anthralin Structure in the drug label.
Pharmacodynamics
There is limited information regarding Anthralin Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Anthralin Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Anthralin Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Anthralin Clinical Studies in the drug label.
How Supplied
There is limited information regarding Anthralin How Supplied in the drug label.
Storage
There is limited information regarding Anthralin Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
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Patient Counseling Information
There is limited information regarding Anthralin Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Anthralin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
- DRITHO-CREME HP®[1]
Look-Alike Drug Names
There is limited information regarding Anthralin Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
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